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前哨淋巴結(jié)切除術(shù)治療早期中期乳腺癌的臨床分析

發(fā)布時間:2018-06-24 來源: 美文摘抄 點(diǎn)擊:


  [摘要] 目的 研究前哨淋巴結(jié)切除術(shù)應(yīng)用于早期中期乳腺癌治療中的臨床效果。方法 方便選取2014年1月—2017年2月間在該院治療的103例早期、中期(T2N0M0)乳腺癌患者,按治療方法不同分為對照組和實(shí)驗組,對照組(53例)采取腋窩淋巴結(jié)清掃術(shù)治療,實(shí)驗組(50例)采用前哨淋巴結(jié)切除術(shù),比較兩組前哨淋巴結(jié)切除率、腋窩引流時間、平均住院時間、并發(fā)癥發(fā)生率。結(jié)果 兩組患者前哨淋巴結(jié)切除率均為100%,實(shí)驗組患者腋窩引流時間(6.9±1.3)d、平均住院時間(7.9±2.1)d均明顯低于對照組(10.3±2.4)d、(12.7±2.7)d(P<0.05);實(shí)驗組患側(cè)出現(xiàn)不同程度的腫脹、疼痛、麻木、活動受限、感覺消退等并發(fā)癥發(fā)生率4.00%、4.00%、8.00%、2.00%、4.00%均明顯低于對照組26.42%、35.85%、41.51%、20.75%、52.83%(P<0.05);術(shù)后隨訪1年兩組均為出現(xiàn)死亡及復(fù)發(fā)。結(jié)論 前哨淋巴結(jié)清掃術(shù)治療早期乳腺癌可以明顯縮短腋窩引流時間及住院時間,降低并發(fā)癥發(fā)生率,提高治療效果,值得推廣應(yīng)用。
  [關(guān)鍵詞] 前哨淋巴結(jié)切除術(shù);早期乳腺癌;治療效果
  [中圖分類號] R4 [文獻(xiàn)標(biāo)識碼] A [文章編號] 1674-0742(2018)01(c)-0097-03
  [Abstract] Objective This paper tries to study the clinical effect of sentinel lymph node resection in the treatment of early stage breast cancer. Methods A total of 103 patients with early and mid-term (T2N0M0) breast cancer who were treated in this hospital from January 2014 to February 2017 were convenient divided into control group and experimental group according to different treatment methods. The control group(53 cases) was treated by axillary lymph node dissection. The experimental group(50 cases) was treated by sentinel lymph node dissection. The resection rate of sentinel lymph nodes, axillary drainage time, average length of hospital stay and complication rate were compared between the two groups. Results The sentinel lymph node resection rate was 100% in the two groups. The average time of hospitalization was(6.9±1.3)d and the average hospitalization time(7.9±2.1)d in the experimental group, significantly lower than that in the control group of (10.3±2.4)d, (12.7±2.7)d(P<0.05). The incidence of complication was 4.00%、4.00%、8.00%、2.00% and 4.00% in the experimental group with different degrees of swelling, pain, numbness, activity limitation and feeling, lower than that of the control group(26.42%, 35.85%, 41.51%, 20.75%, 52.83%, P<0.05). All patients were followed up for one year and without recurrence. Conclusion Sentinel lymph node dissection can shorten the time of axillary drainage and hospitalization time, reduce the incidence of complications and improve the therapeutic effect. It is worthy to be popularized and used.
  [Key words] Sentinel lymphadenectomy; Early breast cancer; Treatment effect
  乳腺癌發(fā)病率呈逐年升高的趨勢,嚴(yán)重威脅著女性的生命健康[1]。以往多采用腋窩淋巴結(jié)清掃術(shù)治療,但是術(shù)后并發(fā)癥較多,且對無腋窩淋巴結(jié)轉(zhuǎn)移患者的生存無明顯益處。近年來有臨床資料指出前哨淋巴結(jié)清掃術(shù)治療早期、中期乳腺癌術(shù)后患者并發(fā)癥發(fā)生率較低,患者生存質(zhì)量明顯改善[2]。因此該研究方便選擇2014年1月—2017年2月間在該院治療的50例早期、中期(T2N0M0)乳腺癌患者作為研究對象,分析了前哨淋巴結(jié)切除術(shù)應(yīng)用于早期乳腺癌治療中的臨床治療效果,現(xiàn)匯報如下。
  1 資料與方法
  1.1 一般資料

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