[摘要] 目的 觀察分析陰虛風(fēng)動(dòng)證室性早搏患者動(dòng)態(tài)心電圖的特征性改變。 方法 選取2011年11月～2016年8月于中國中醫(yī)科學(xué)院廣安門醫(yī)院（以下簡稱“我院”）就診的室性早搏之陰虛風(fēng)動(dòng)證患者90例作為室早組，并選取我院同期健康體檢者30名作為對照組。所有受試者均行24 h動(dòng)態(tài)心電圖檢查，觀察分析兩組患者的平均心率、最慢心率、心率變異性（HRV）指標(biāo)、室早組患者晝夜室早頻次、室早組患者中醫(yī)證候分級與HRV指標(biāo)的相關(guān)性。 結(jié)果 室早組的平均心率、最慢心率均高于對照組（P < 0.05）；室早組全部竇性心搏R-R間期的標(biāo)準(zhǔn)差（SDNN）、每5分鐘節(jié)段的正常R-R間期平均值標(biāo)準(zhǔn)差（SDANN）、兩個(gè)相鄰的R-R間期差值>50 ms心率總數(shù)占全部分析信息期間內(nèi)的心率數(shù)的百分比例（PNN50）、24 h連續(xù)正常的 R-R間期差值均方的平方根（RMSSD）、HRV三角指數(shù)值均低于對照組（P < 0.05）；室早組患者夜間的室性早搏頻次高于晝間（P < 0.05）；室早組患者中醫(yī)證候分級與年齡呈正相關(guān)，與SDNN、SDANN、PNN50、RMSSD、HRV三角指數(shù)均呈負(fù)相關(guān)。 結(jié)論 室早組患者的室早頻次夜間高于晝間，且HRV值低于對照組，推測陰虛風(fēng)動(dòng)證室性早搏的發(fā)生與自主神經(jīng)功能紊亂相關(guān)，且以迷走神經(jīng)功能降低為主。
　　[關(guān)鍵詞] 室性早搏；陰虛風(fēng)動(dòng)證；動(dòng)態(tài)心電圖；心率變異性
　　[中圖分類號] R541.7 [文獻(xiàn)標(biāo)識碼] A [文章編號] 1673-7210（2018）02（c）-0141-04
　　Analysis on the characteristics of dynamic electrocardiogram of premature ventricular contractions with syndromes of stirring wind due to yin deficiency
　　CHEN Jin1，2 ZHANG Limei1 SONG Qingqiao1 DU Bai1
　　1.Department of Cardiology， Guang"anmen Hospital， China Academy of Chinese Medical Sciences， Beijing 100053， China； 2.Clinical Medical College， Beijing University of Chinese Medicine， Beijing 100029， China
　　[Abstract] Objective To observe the characteristic changes of dynamic electrocardiogram in patients who were diagnosed as premature ventricular contractions with syndromes of stirring wind due to yin deficiency. Methods From November 2011 to August 2016， 90 patients who were diagnosed as premature ventricular contractions with syndromes of stirring wind due to yin deficiency in Guang"anmen Hospital， China Academy of Chinese Medical Sciences （“our hospital” for short） were selected as the premature ventricular contraction group， and 30 healthy subjects in our hospital were selected as the control group. All subjects underwent 24 hours dynamic electrocardiogram. The average heart rate， slowest heart rate， heart rate variability （HRV） of the two groups and the number of premature ventricular contraction in morning and night of premature ventricular contraction group， the correlation between TCM syndrome classification and HRV index in the premature ventricular contraction group were observed and analyzed. Results The levels of the average heart rate and the slowest heart rate in premature ventricular contraction group were all higher than those in control group （P < 0.05）. The levels of standard deviation of NN intervals （SDNN）， standard deviation of average 5 min NN intervals （SDANN）， percentage of differences exceeding 50 ms between adjacent normal number of intervals （PNN50）， square root of the mean squared differences of successive RR interval （RMSSD） and HRV trigonometric index in premature ventricular contraction group were lower than those in control group （P < 0.05）. The premature ventricular contraction frequency of premature ventricular contraction group in the night was more than that in the morning （P < 0.05）. The syndrome classification of traditional Chinese medicine in premature ventricular contraction group was positively correlated with age， which was negatively correlated with SDNN， SDANN， PNN50， RMSSD， HRV triangular index. Conclusion The premature ventricular contraction frequency of patients in premature ventricular contraction group in the night is more than that in the morning， and the HRV is lower than control group. It is speculated that the occurrence of premature ventricular contraction with syndrome of stirring wind due to yin deficiency is positively related to autonomic nerve dysfunction， mainly vagus function decline.

相關(guān)熱詞搜索：陰虛 心電圖 特征 分析 動(dòng)態(tài)